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Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation which makes them planning to benefit from naltrexone, in contrast to about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are presently available online ( within the journal Neuropsychopharmacology and will also be published in an upcoming print edition with the journal. Using two separate drugs to lose weight naturally can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people who go through it you ought to err to the side of caution and let the FDA do its job and demand some investigation be done in order that the public understands the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on their medications. Researchers found that participants taking this drug to get a year, dropped a few pounds within four weeks and have kept the extra weight off through the 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which might be made up of many active ingredient, which can make them more efficient and safer. Combo-pilling will be the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that at the time of right now there aren't long term prescription diet pills that have been approved by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise blood pressure level and heart rate, and mustn't be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high blood pressure level, and also by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. 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